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Operant Scientific
Discovery, process R&D, green chemistry

Chemistry that answers real questions.

Our R&D group runs concurrent programmes — discovery-stage screening, process R&D for validated molecules, and green-chemistry optimisation. Every route goes through a green-chemistry review before we commit to scale-up.

Programme types
Discovery · Process R&D · Green chemistry
Team
12 PhD chemists, 8 M.Pharm analytical
Publications
Peer-reviewed papers under Operant Publications
Green metric
PMI review on every route, target ≤ 30
Process

Five stages from brief to delivery.

Timelines vary by molecule and scope; the shape below applies to every engagement.

  1. Step 01

    Programme scoping

    Discovery, process, or green-chemistry — clear success criteria.

  2. Step 02

    Literature + IP

    Structured literature and patent-landscape review.

  3. Step 03

    Lab experiments

    DoE-driven experimentation with in-line analytical support.

  4. Step 04

    Scale-up feasibility

    Assess safety, throughput, and cost before committing to pilot.

  5. Step 05

    Tech report

    Client-facing report with data package, IP position, and next-step plan.

Equipment & governance

The specific tools, standards, and headcount.

R&D lab capability

  • R&D lab bays×6

    Independent bays with fume hood and reactor

  • Automated reactor stations×4

    Chemspeed / Mettler-Toledo integration

  • Analytical rapid-access queue×1

    Same-day HPLC and NMR turnaround for R&D samples

  • DoE + Lean-Six-Sigma trained team

    Every senior chemist certified

Representative case

One example, real numbers.

Recent engagement

Biocatalytic route eliminated a hazardous reagent.

Client wanted to remove a controlled reagent from an existing route. R&D group delivered a biocatalytic alternative in 12 weeks with equivalent yield.

Reagent removed
Yes
Client
EU generics
Timeline
12 weeks
Yield
Equivalent
Read the full caseRepresentative case — full attribution under NDA.

R&D and innovation — capability deck

A ten-page PDF written by our subject-matter lead for this capability. Delivered by email within one business day, always signed by a director.

  • Small-molecule discovery, process R&D, and green-chemistry programmes
  • 12 permanent PhD chemists with DoE and Lean-Six-Sigma training
  • Every route goes through a green-chemistry review before scale-up

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